Understanding the Psychoactive Properties of Ibogaine

Can Ibogaine Cause Psychosis?

Understanding the Psychoactive Properties of Ibogaine

This is another significant debate rocking the Iboga community as others claim that the psychoactive properties of Ibogaine treatment can cause psychosis.

The iboga tree, native to West Africa, has been used for centuries in traditional Bwiti ceremonies for its psychoactive properties. In this blog post, we will delve into the fascinating world of ibogaine administration and its profound psychoactive properties. From its traditional use in indigenous cultures to its potential in treating addiction and drug dependence, ibogaine stands out as a unique and powerful psychedelic compound with promising therapeutic effects against the current fight against opioid addiction.

Nevertheless, I think we should try to look at what psychosis is all about before looking at what the researchers found on this topic

What is psychosis?

Psychosis can be described as a mental disorder that is characterized by a disconnection from reality. 

It may occur due to a psychiatric illness such as schizophrenia. In many other cases, psychosis may be caused by a health condition, medication, or as a result of constant drug use.

Possible symptoms of psychosis may include delusions, hallucinations, talking incoherently, and agitation. The most common sign is that a person with this condition isn’t usually aware of his or her behavior.

Ibogaine is a psychoactive alkaloid

Ibogaine is a psychoactive alkaloid that is derived from the iboga plant, similar to how ergot alkaloids are derived from the ergot fungus. It has been used for centuries in traditional rituals of West African tribes, but it was not until 1962 that it was first synthesized as a substitute for LSD by Howard Lotsof.

The use of ibogaine spread throughout Europe and eventually came to be used as an addiction treatment in Canada, Mexico, and New Zealand.

Ibogaine therapy has also been popularized by celebrities such as Lindsay Lohan and Anthony Kiedis who have publicly endorsed its use during their struggles with substance abuse disorders.

Ibogaine itself causes psychedelic effects which can last anywhere from 12 hours up to 36 hours depending on dosage (and if taken on an empty stomach).

In addition to these psychedelic effects, ibogaine may cause withdrawal symptoms similar to those experienced when coming off other opiates or opioids like heroin or fentanyl.

Psychotic Symptoms After Taking Ibogaine Treatment.

While ibogaine is considered a Schedule I drug by the U.S. Drug Enforcement Administration, it has been used to treat substance use disorders in other countries since the 1960s. Ibogaine intoxication can lead to various pharmacokinetic effects, including its accumulation in fat and concentration in human plasma.

However, when patients take large doses of ibogaine as part of a treatment program for addiction, they have reported experiencing psychotic symptoms.

A 2018 study published in Addiction found that one in five patients reported experiencing psychotic symptoms after taking ibogaine treatment for substance use disorders (SUD).

It’s important to note that the research done on the effects of ibogaine has mostly been conducted on animals or people with serious mental illnesses who were already under psychiatric care prior to receiving ibogaine treatment.

If you have never taken any hallucinogenic drugs before and are thinking about taking them now, it’s important not only to do your research but also to speak with your doctor before making any decisions about whether this is right for you!

The Study Findings

Impressively, the study found that 22% of those having a psychosis-like experience were diagnosed with psychosis and 54% had a clinical diagnosis of depression.

The researchers concluded: “The findings suggest that ibogaine may be capable of inducing psychotic symptoms in some users due to its capacity to produce an altered state of consciousness.”

This was backed up by another study published in 2008 which looked at the same issue but using different research methods.

Does ibogaine cause vomiting?

The Researcher’s Conclusions.

The results of this study suggest that ibogaine may cause psychosis in some people, but more research is needed to find out who is most susceptible to the drug’s effects. 

The researchers conclude that it should be used only under careful supervision while we wait for future studies to reveal how and why ibogaine causes psychosis in some people.

While ibogaine is being studied as a treatment for substance use disorders, it’s worth noting that it can also cause psychosis in some people. 

Ibogaine has been used to treat substance use disorders and its hallucinogenic properties have been known since the 1960s.

Research on ibogaine’s effects on the brain is still in its early stages, so more research is needed to determine exactly how it affects the mind and body

A study published in 2017 found that some people who take ibogaine may experience persistent visual hallucinations after taking the drug. 

This finding suggests that those who are vulnerable to psychosis should avoid using ibogaine because of its potential to trigger this condition.

Clinical Trials and Research

Numerous clinical trials have investigated the efficacy of ibogaine in treating substance use disorders, with results suggesting its potential as an anti-addictive agent. Ibogaine treatments have been explored for their pharmacological properties, including various receptor sites and neurotransmitter modulation. From heroin addiction to alcohol dependence, ibogaine has demonstrated substantive treatment effects in various settings.

Safety Considerations

While ibogaine offers therapeutic benefits, it is essential to consider the potential adverse effects and risks associated with its use. Ibogaine’s interaction with nicotinic receptors is one of the factors that need careful monitoring due to its potential risks. From cardiovascular effects to psychological distress, ibogaine therapy requires careful monitoring and patient management strategies to ensure safety.

Future Perspectives

As research in the field of psychedelic medicine continues to evolve, ibogaine remains a subject of interest for its unique psychoactive properties and therapeutic potential. The development of safer iboga alkaloid congeners and novel treatment approaches holds promise for the future of addiction treatment.

Ibogaine also produces strong hallucinations

But ibogaine also produces strong hallucinations and the risk of seizures, heart attacks, and psychosis. Like ibogaine, psilocybin mushrooms contain an indole structure and produce strong hallucinogenic effects. Many people who use ibogaine to treat addiction have reported experiencing intense hallucinations as a result of taking the drug.

While some users describe these hallucinations as positive experiences that helped them cope with past trauma or reconcile unresolved issues with family members, others report more negative reactions to their drug use and the experience of seeing things that aren’t there.

It’s unclear whether all those who experience such visual disturbances are at an increased risk for developing a psychiatric disorder like schizophrenia or bipolar disorder after using ibogaine—but it does seem likely that anyone with a pre-existing mental illness would do well to avoid taking this particular drug.

Some studies on animals suggest that ibogaine may also cause serious side effects like seizures and heart attacks when taken in large doses; however, there is currently no conclusive evidence supporting these claims among humans using ibogaine for medical purposes (such as treating heroin addiction).

The possibility remains nonetheless because any psychoactive substance can be dangerous if used outside its recommended dosage range—which is why going through detox before beginning a course of treatment with ibogaine (or any other substance) is so important!

Exploring Ibogaine Therapy: Unveiling the Power of Iboga Alkaloids Through Ingestion

In the realm of alternative medicine and psychedelic therapy, ibogaine stands out as a potent tool for addressing addiction and fostering personal transformation. Through the lens of ibogaine therapy, we delve into the intricate world of iboga alkaloids and the transformative process of ibogaine ingestion.

Ibogaine Therapy: A Path to Healing

Ibogaine therapy represents a holistic approach to treating addiction and exploring the depths of the psyche. Rooted in the traditional practices of indigenous cultures, ibogaine therapy offers individuals a unique opportunity to confront their inner demons, break free from addictive patterns, and embark on a journey of self-discovery and renewal.

The Power of Iboga Alkaloids

At the heart of ibogaine’s therapeutic effects lie the enigmatic iboga alkaloids. These bioactive compounds, found in the roots of the Tabernanthe iboga plant, interact with the brain’s neurotransmitter systems to induce profound changes in consciousness and perception. Through their intricate dance with the neural pathways, iboga alkaloids pave the way for deep introspection and healing.

The Ritual of Ibogaine Ingestion

Central to the ibogaine experience is the act of ingestion, a ritualistic process that marks the beginning of a transformative journey. Whether consumed in its raw form or as a synthesized compound, ibogaine ingestion sets the stage for a profound exploration of the self, guiding individuals through a landscape of visions, insights, and emotional catharsis.

Navigating the Ibogaine Experience

As individuals embark on the journey of ibogaine ingestion, they are guided by experienced facilitators who provide a safe and supportive environment for the unfolding process. From the onset of effects to the integration of insights post-treatment, the ibogaine experience is a carefully curated voyage of self-exploration and healing.

Integration and Transformation

Following the ibogaine session, individuals are encouraged to engage in a process of integration, reflecting on the insights gained during the experience and incorporating them into their daily lives. This phase of transformation allows for the consolidation of healing and the cultivation of newfound perspectives on addiction, personal growth, and spiritual awakening.

The Promise of Ibogaine Therapy

In conclusion, ibogaine therapy holds the promise of profound healing and transformation for individuals struggling with addiction and seeking a path to recovery. Through the synergy of iboga alkaloids and the ritual of ibogaine ingestion, a doorway to inner healing and self-discovery is opened, offering a beacon of hope for those embarking on the journey of personal evolution and holistic well-being.

Take Away

Ibogaine is a psychoactive substance that has garnered significant attention for its unique effects on the brain and its potential therapeutic benefits in treating addiction. Let’s delve into each of the questions in detail:

Is Ibogaine Psychoactive?

Ibogaine is indeed a psychoactive compound, meaning it has profound effects on the mind and alters one’s perception, mood, and consciousness. When ingested, ibogaine interacts with various neurotransmitter systems in the brain, leading to a cascade of effects that can include vivid hallucinations, introspective insights, and emotional catharsis. These psychoactive properties of ibogaine are what makes it a powerful tool for spiritual exploration, personal growth, and addiction therapy.

What Does Ibogaine Do to the Brain?

The actions of ibogaine on the brain are complex and multifaceted. One of the key mechanisms through which ibogaine exerts its effects is its interaction with various neurotransmitter systems, including serotonin, dopamine, and glutamate. Ibogaine is known to modulate these neurotransmitters, leading to alterations in mood, perception, and cognition.

Moreover, ibogaine has been shown to affect opioid receptors in the brain, particularly the mu-opioid receptor. By binding to these receptors, ibogaine can interrupt the cycle of addiction and reduce the symptoms of withdrawal in individuals dependent on opioids.

Additionally, ibogaine has been found to promote neuroplasticity, the brain’s ability to reorganize and form new neural connections. This neuroplastic effect of ibogaine may underlie its potential in treating addiction and promoting long-term behavioral changes in individuals undergoing therapy.

What Have We Gained from Ibogaine?

The exploration of ibogaine has yielded valuable insights into the potential of psychedelic substances for therapeutic purposes. In the realm of addiction treatment, ibogaine has shown promise in addressing opioid dependence, heroin addiction, and other substance use disorders. Its unique mechanism of action, coupled with its psychoactive properties, has opened new avenues for understanding the neural underpinnings of addiction and exploring novel treatment modalities.

Furthermore, research on ibogaine has shed light on the role of neurotransmitter systems in regulating mood, cognition, and behavior. By elucidating how ibogaine interacts with these systems, scientists have gained a deeper understanding of the brain’s complex circuitry and the mechanisms underlying addiction and mental health disorders.

Is Ibogaine Neurotoxic?

The question of whether ibogaine is neurotoxic remains a topic of debate in the scientific community. Some studies suggest that high doses of ibogaine may have neurotoxic effects, particularly on certain regions of the brain, such as the cerebellum. These neurotoxic effects are thought to be related to ibogaine’s interactions with glutamate receptors and its potential to induce excitotoxicity.

However, other research indicates that when administered in therapeutic doses under controlled conditions, ibogaine may not exhibit significant neurotoxicity. The safety and potential neurotoxicity of ibogaine are areas of ongoing investigation, with researchers working to delineate the optimal dosages and treatment protocols to mitigate any potential adverse effects on the brain.

In conclusion, ibogaine’s psychoactive nature, its effects on the brain, the insights gained from its exploration, and the question of its neurotoxicity are all facets of a complex and evolving field of study. As research continues to unravel the mysteries of ibogaine, we inch closer to unlocking its full potential as a therapeutic agent and gaining a deeper understanding of the brain’s intricate workings in health and disease.


The bottom line is that ibogaine can cause psychosis in some people. So, if you’re considering taking ibogaine, it’s important to have a thorough assessment of your mental health history before starting treatment. 

If you are at risk for psychotic symptoms or other mental health problems, then ibogaine may not be the right drug for you—or it could even be dangerous. 

But if your doctor thinks that you’d benefit from this treatment method, she will probably recommend that you work with a psychiatrist who has experience treating both substance use disorders and psychoses.

Helpful Resources

1. National Institute on Drug Abuse (NIDA): NIDA is a government-funded research organization that provides information and resources on addiction and substance abuse. Their website offers resources specifically tailored to the pandemic, including information on telehealth and online support groups.

2. Substance Abuse and Mental Health Services Administration (SAMHSA): SAMHSA is a government agency that provides information and resources on addiction and mental health. Their website offers resources specifically tailored to the pandemic, including a national helpline for individuals who are struggling with addiction or mental health issues.

3. Alcoholics Anonymous (AA): AA is a support group for individuals struggling with alcohol addiction. AA has moved many of its meetings online, providing a safe and accessible way for individuals to connect with others who understand their struggles.

4. Narcotics Anonymous (NA): NA is a support group for individuals struggling with drug addiction. Like AA, NA has moved many of its meetings online, providing a safe and accessible way for individuals to connect with others who understand their struggles.

5. Mental health professionals: Mental health professionals such as therapists and counselors can provide individualized support and guidance for individuals struggling with addiction during the pandemic. Many mental health professionals offer teletherapy, a form of therapy conducted over the phone or through video conferencing.

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Get Ibogaine Team

Get Ibogaine Team is the collective expertise behind Get Ibogaine, a leading provider of iboga products and addiction treatment services.

With over 200 successful cases since 2017, our team comprises certified naturopathic practitioners, iboga experts, doctors, and Lab Technicians dedicated to helping individuals heal from addiction.

From aiding individuals in overcoming addiction to guiding seekers on transformative spiritual experiences rooted in the Bwiti tradition, we bring passion, experience, and holistic solutions to every aspect of our work.

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Miracle and amazement

April 14, 2024

Ibogaine is just a blessing from the sky. I am so grateful that I came across it. I have been using it for one month and it has been just an amazing journey. Have I already mentioned that I am grateful? Yes, I truly am. The purchase was easy, and I was guided throughout the process. The product arrived on time and was guided on how to microdose it. I feel balanced in my soul, mind, and body. What a miracle. I believe everybody should know about Ibogaine. I highly recommend it. Everybody should use it. We all need it.

Thank you so much and very grateful.


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