Iboga and ibogaine are two plant-based substances that have gained popularity as a result of their potential therapeutic effects on addiction and mental health. While they are both derived from the same plant, the Tabernanthe iboga shrub, they differ significantly in their chemical composition and effects on the body.
The use of iboga and ibogaine in addiction treatment highlights their potential in reducing or eliminating addiction to opioids and other substances, underscoring their significance in therapeutic interventions.
In this article, we will look at the differences between iboga and ibogaine, including their chemical structures, physiological effects, and potential therapeutic applications.
Let’s dive in…
Ibogaine and Iboga Root Bark’s Chemical Composition
The root bark of the West African shrub Tabernanthe iboga, known for its iboga root, is the source of iboga and ibogaine. Among the alkaloids found in the root bark are ibogaine hydrochloride, ibogamine, and noribogaine.
The most well-known and researched of these alkaloids is ibogaine hydrochloride, a psychoactive substance with potential therapeutic effects on addiction and mental health conditions. ibogaine is derived from ibogamine, the parent compound of the iboga alkaloids.
On the other hand, a natural plant extract rich in alkaloids such as ibogaine, ibogamine, and noribogaine is iboga. It is usually consumed in its natural form, either as a tea or by chewing the root of the iboga plant.
The use of iboga root bark, being the oldest known form of the visionary iboga experience, is emphasized for its safety and effectiveness.
The different effects of ibogaine treatment on your body
In many ways, the body’s response to iboga and ibogaine is similar, but there are some significant differences. Intense psychoactive effects such as hallucinations, altered perceptions of time and space, and profound introspection have been associated with both substances.
Additionally, ibogaine has been noted to attenuate opioid withdrawal, offering potential benefits in the context of addiction treatment.
Ibogaine, however, is considered to be more potent and has a longer-lasting effect than iboga. The effects can persist for several days after ingestion due to its half-life of approximately 24 hours. In contrast, iboga’s effects typically last an average of 12 hours.
Furthermore, there is a notable difference in how iboga and ibogaine affect the cardiovascular system. Potentially hazardous heart effects, such as changes in heart rate and rhythm, have been observed with ibogaine use. This has led to concerns about its safety, particularly for individuals with pre-existing heart conditions.
Therapeutic Uses in Treating Addiction
Both the potential therapeutic uses of iboga and ibogaine have been investigated, particularly in the treatment of addiction and mental health conditions.
In this regard, ibogaine therapy has received the most attention. Potential benefits in treating addiction, including drug addiction opiate addiction, and mental health conditions have been demonstrated. The brain’s reward system can be reset by it, reducing cravings and withdrawal symptoms, and promoting feelings of well-being and connection.
The potential use of ibogaine for mental health conditions such as depression, anxiety, and post-traumatic stress disorder (PTSD) has also been investigated. While more research is needed in this area, preliminary findings are promising.
Less attention has been paid to iboga in the scientific literature, but it is also believed to have therapeutic potential.
For centuries, some traditional cultures in West Africa have used iboga in spiritual and healing ceremonies. It is believed to have a range of benefits, including physical and emotional healing, clarity and insight, and assisting individuals in connecting with their higher selves.
Iboga is also being studied for its potential application in ibogaine treatment for addiction and mental health disorders. While more research is needed, some experts believe that the full spectrum of alkaloids found in iboga, including the total alkaloid extract, may be responsible for its distinct therapeutic effects that differ from those produced by ibogaine alone.
However, it is important to note that both iboga and ibogaine are still illegal or restricted substances in many countries, and their use should always be supervised by trained professionals.
Is it iboga or ibogaine?
Ibogas (Tabernante iboga) are plants used in some African cultural activities. The substance causes hallucinations of the mind. Iboga contains chemicals that stimulate the brain. Its bark is derived by producing ibogaine in its root.
How many people have died from ibogaine?
During 18 months, there were a total of 18 fatalities caused by ibogaine ingestion. Six patients died of heart problems or cardiac arrests. Its bans have slowed the development of science.
What is another name for iboga?
Igaea (12-methoxyibogamines) is a psychoactive indole alkaloid found in the Western African shrub Tabernanthe iboga.
What are the effects of iboga?
Ibogaine is potentially dangerous. Many reports have been published regarding cardiac events caused by ibogaine treatment. Other side effects include nausea and tremors, (not usually), psychosis, mania, seizure, and comas.
Ibogaine HCL is the purified form of the Iboga root
This product was produced by only an industry-based company that has 99% or more pure water, therefore containing no harmful toxins.
Iboga can also be given in a correct dosage because its impureness can only be estimated. It’s incredibly dangerous in too high doses.
Psychoactive effects
Ibogaine originates from the root of Tabernanthe iboga, an herb that possesses psychedelic effects. Ibogan’s traumatic experiences can occur over 2 stages: visionary and introspection. The visionary stage is described as neurogenic and refers to its dreamlike nature and can last 4 or 6 hours and can be seen in the video below.
The second stage of introspection has a psychological effect. C.S.citations are required, this will help people overcome their fears or feelings of anger.
Total Alkaloid Extract (TA)
Alkaloids are a combination of the pro and contra of both ibogas and ibogaine. All active compounds and alkaloids can be extracted from iboga bark and concentrated in brown clumped particles that may sometimes be dissolved in a dark solution. Therapy doses range between 1 and 5 g each.
Most of it is ibogaine and many are psychoactive as well. Some of the research is limited and others may be unexplored. So you will be taking all the chemicals that can supplement Ibogaine with less pain or discomfort.
Ibogaine HCL
Don’t use whole leaf bark as the tree contains traces of alkaloids. Some vendors are selling whole root, but besides the small amount of bark in powdered whole root this product is usually inactive and is a waste of funds. Avoid providers using Iboga because they contain toxic and non-measurable substances that cause urinating and are therefore unsafe.
Iboga Root is pure guesswork and useless, also full of unknown toxins
Ibogaine HCL has an 8% purity, it’s easy to use, in appropriate doses, safe, accurate, and reliable. Also safe from harmful substances. Although almost all Ibogaine providers claim to have used Ibogaine HCL, unfortunately, it doesn’t exist.
Demand verification of the use of Ibogaine HCL before selecting an organization. Ibogaine is extremely effective in dealing with both addiction and withdrawal. Following Ibogaine treatment, the client may notice that they have virtually disappeared physical cravings as well as no physical withdrawal symptoms such as sweating or tremors.
Design of ibogaine analogs
Ibogaine is the major constituent of the roots of Tabernanthe iboga, the shrub widely found in West and Central Africa. Ibogaine has been shown to decrease cocaine and morphine self-administration in laboratory animals.
Similarly, the substance inhibits nicotine-related rewards in animals, but the dietary supplement reduces the craving in humans. In addition, it has been suggested to be useful in treating the recurrence of drug addiction. Ibogaine and Ibogaine fragments. This study aimed to develop synthetic ibogaine-like compounds that may be more effective than their parent compound.
Ibogaine Therapy
Ibogaine contains a naturally forming psychoactive substance extracted from the roots of plants called Iboga. Iboga (Tabernanthe iboga) belongs to the Apocynaceae family. It has the largest amount of ibogaine, an indole alkaloids.
Ibogan is an indigenous shrub that extends throughout the tropical hot and humid African region from Cameroon to Congo. However, Gabon, the country on the African coast, is where Iboga thrives.
The roots of Tabernacanthe manei are also rich in the alkaloid Ibogaine. This is an alkaloid that can be absorbed by the body by the cellular body. Voacanga Africana is a widespread shrub containing Ibogaine. Ervatamiia orientalis produces Ibogaine in Australian leaf.
Comparing the Safety of Iboga and Ibogaine Therapy
Both Iboga and Ibogaine require good supervision and care. Iboga is much safer and safer after a thorough medical exam.
Psychedelic Neuroscience
In Progress on Brain Research 2018 by:
Depression and Mental Health Conditions
Some anti-depressants in Ibogaine may result from a sigma-like receptor triggered in a person’s brain (12). Researchers reveal that ibogaine has the potential to stimulate the receptor it activates. Tabernanthine has been shown to act as an active ingredient in sigma-2, and a combination of alkaloids in the form of iboga can be useful in combatting disorders including depression.
Pharmacology and Pharmacokinetics of Ibogaine
Ibogaine is unique to the human body with complex pharmacological properties and is widely receptive for various receptor sites, as either an antagonist or an agonist. These are characteristic clinical features. These targets are NMDA, nicotinate – and opioids. NMDA binds messenger proteins such as glycine and glutamate.
Glutamate is considered the main neurotransmission booster in the CNS. The glutamate neuron is the principal neuronal transmitting cell in the cortex, which regulates cognitive abilities, memory, and emotion.
Iboga Root Bark and Iboga TA are much safer
However, using a TA extract from the root of the Iboga plant can be very effective, as Noribogine is the most harmful metabolite. It is important to keep alkaloids in mind like tabernanthe (13 methionoxy – ibogamine), ibogamine & cytidine. TA extract also allows dosage as precise as Ibogaine alone while receiving the advantages of each of the alkaloids and their interactions. A low dose of ibogaine also has less side impact.
Ibogaine and the Treatment of Opiate Addiction
Iboga (Tabernanthe iboga)
The perennial rainforest shrub T. Iboga also referred to as iboga, is found in central West Africa. Its height is 1.5–2 meters. It has yellowish or pink flowers turning out sweet fruits without alkaloids.
The plant is a sacrament of power in the Buddhist faith, where the roots are utilized as an ancestors’ bridge during religious celebrations. The root in small amounts can be eaten by hand in small quantities (amount 5 mg kg)
Ibogaine Background and Potential as a Treatment for Alcohol Use Disorder
Ibogaine is a secondary alkaloid found in the roots of the tabernanthe iboga plant that was traditionally used for ritual purposes in Central Africa. In recent decades several studies have demonstrated ibogaine’s effectiveness as a treatment for opioid dependency. The therapeutic response rate in recent observational studies of patients with opioid use is promising.
Pain and Addiction
The roots of iboga (Apocynaceae) (The Bernanthe iboga Roots in Central Africa) are commonly used as an inducer of a hallucinogenic experience.
These hallucinations were reported to give insight into the cause of sterility and assist the village people in establishing contacts. Indole alkaloids Ibogaine and its metabolites Norinbogaine were discovered by Deborah Mash in an effort to treat a number of chronic pain issues at Miami BrainBank. St. Kitt’s heroin addiction trial was very successful.
Conclusion: Iboga’s Role in Spiritual Growth
To conclude, iboga and ibogaine are two plant-based substances that have received attention due to their potential therapeutic effects on addiction and mental health. While they are both derived from the same plant, they differ significantly in their chemical composition and effects on the body.
Ibogaine is a synthetic derivative of ibogamine that is thought to be more potent and last longer than ibogaine. It has, however, been shown to have potentially dangerous effects on the heart, raising concerns about its safety.
Iboga, on the other hand, is a natural plant extract that contains a variety of alkaloids such as ibogaine, ibogamine, and noribogaine. It is thought to be safer for the cardiovascular system than ibogaine, but its full range of effects is still being studied.
Both iboga and ibogaine have potential therapeutic uses, particularly in the treatment of addiction and mental health conditions. While more research is needed in this area, early studies have shown promising results.
Overall, iboga and ibogaine are fascinating substances that have the potential to unlock new approaches to healing and personal growth. As more research is conducted, we will likely continue to uncover new insights into their mechanisms of action and potential therapeutic applications.
Additionally, their role in facilitating spiritual growth, as seen in the Bwiti spiritual tradition, underscores their potential beyond physical healing, offering pathways to profound personal and spiritual development.
